منابع مشابه
Coinfection of Human Herpesviruses 6A (HHV-6A) and HHV-6B as Demonstrated by Novel Digital Droplet PCR Assay
The human herpesviruses HHV-6A and HHV-6B have been associated with various neurologic disorders partly due to the detection of elevated viral DNA levels in patients compared to controls. However the reported frequency of these viruses varies widely, likely reflecting differences in PCR methodologies used for detection. Digital droplet PCR (ddPCR) is a third generation PCR technology that enabl...
متن کاملPrevalence of human herpesvirus 6A and 6B during pregnancy.
The aim of the present study was to assess the frequency of human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HHV-6B) infection during pregnancy. 100-100 blood samples were collected from pregnant and non-pregnant women, then nucleic acid was isolated from both plasma and leukocytes fraction. Nested and real-time PCR were used to detect and differentiate HHV-6A and HHV-6B DNA and to deter...
متن کاملFeatures of Human Herpesvirus-6A and -6B Entry
Human herpesvirus-6 (HHV-6) is a T lymphotropic herpesvirus belonging to the Betaherpesvirinae subfamily. HHV-6 was long classified into variants A and B (HHV-6A and HHV-6B); however, recently, HHV-6A and HHV-6B were reclassified as different species. The process of herpesvirus entry into target cells is complicated, and in the case of HHV-6A and HHV-6B, the detailed mechanism remains to be elu...
متن کاملHuman Herpesviruses 6 and 7
The identification of human herpesvirus (HHV) 6 (HHV-6) and 7 (HHV-7) was first reported in 1986 and 1990, respectively. HHV-6 was isolated initially from the blood of several immunodeficient adults, including some with acquired immunodeficiency syndrome (AIDS) (1). The existence of HHV-7 was first revealed in the blood of a healthy, human immunodeficiency virus (HIV)-negative adult (2). Extens...
متن کاملHuman herpesvirus 6B genome sequence: coding content and comparison with human herpesvirus 6A.
Human herpesvirus 6 variants A and B (HHV-6A and HHV-6B) are closely related viruses that can be readily distinguished by comparison of restriction endonuclease profiles and nucleotide sequences. The viruses are similar with respect to genomic and genetic organization, and their genomes cross-hybridize extensively, but they differ in biological and epidemiologic features. Differences include in...
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ژورنال
عنوان ژورنال: Microbiology Spectrum
سال: 2016
ISSN: 2165-0497
DOI: 10.1128/microbiolspec.dmih2-0007-2015